Late-Breaking Research
Witness First-Time Presentations of Major Clinical Trials and Impactful Science Research
Get a front-row seat to the latest breakthroughs that will change your practice and revolutionize patient care around the world!
| PARTNER 3 Low-Risk Five-Year Clinical and Echocardiographic Outcomes from The PARTNER 3 Low-Risk Randomized Trial Martin B. Leon |
EVOLUT Low Risk Four-Year Outcomes from the EVOLUT Low Risk Trial Michael J. Reardon |
| WATCH TAVR Safety and Efficacy of Left Atrial Appendage Occlusion at the Time of Transcatheter Aortic Valve Replacement — The WATCH TAVR Trial Samir R. Kapadia |
ALIGN-AR Initial Outcomes of the JenaValve Trilogy Transcatheter Aortic Valve Replacement System in High-Risk Patients with Symptomatic Severe Native Aortic Regurgitation Vinod H. Thourani |
| LIFE-BTK Primary Outcomes of the Esprit™ BTK Drug-Eluting Resorbable Scaffold for the Treatment of Infrapopliteal Lesions: The LIFE-BTK Randomized Controlled Trial Ramon L. Varcoe |
AGENT IDE Primary Outcomes of a Pivotal Multicenter Randomized Trial Comparing the AGENT Paclitaxel-Coated Balloon with Conventional Balloon Angioplasty for In-Stent Restenosis Robert W. Yeh |
| T-PASS Less Than 1-month Dual Antiplatelet Therapy Followed by Ticagrelor Monotherapy after Coronary Drug-Eluting Stent Implantation for Acute Coronary Syndrome: The T-PASS Randomised Trial Myeong-Ki Hong |
PICSO-AMI-I Pressure-Controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction: The Randomized PICSO-AMI-I Trial Giovanni Luigi De Maria |
| TRISCEND II A Randomized Trial of Transcatheter Tricuspid Valve Replacement in Patients With Severe Tricuspid Regurgitation: The TRISCEND II Trial Susheel K. Kodali |
TRILUMINATE Quality of Life After Transcatheter Tricuspid-Valve Repair vs. Medical Therapy in Patients with Severe Tricuspid Regurgitation: Results from the Randomized TRILUMINATE Pivotal Trial Suzanne V. Arnold |
| VIVA Transcatheter versus Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Small Aortic Annuli: A Randomized Clinical Trial (the VIVA Trial) Josep Rodés-Cabau |
CLASP IID One Year Outcomes from a Randomized Comparison of Transcatheter Edge-to-Edge Repair Systems For Degenerative MR: The CLASP IID Trial and Registry Robert L. Smith & Firas Zahr |
Five-year Echocardiographic Outcomes From The PARTNER 3 Low-risk Randomized Trial |
Tendyne SUMMIT Pivotal Trial Roll-In and MAC Arm Outcomes |
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TRILUMINATE Pivotal: Outcomes of Both Randomized and Single-arm Subjects with Transcatheter Tricuspid Valve Edge-to-Edge Repair for Tricuspid Regurgitation |
One-Year Outcomes after Amulet or Watchman/FLX Device for Percutaneous Left Atrial Appendage Closure: a Pre-Specified Analysis of the SWISS-APERO Randomized Clinical Trial |
One-Year Outcomes with Fourth-Generation Mitral Valve Transcatheter Edge-to-Edge Repair from EXPAND G4 |
Sirolimus-Coated Balloon Versus Paclitaxel-Coated Balloon for the Treatment of Drug-Eluting Stent In-Stent Restenosis: A Prospective, Multicenter, Randomized Trial Miaohan Liu |
The Primary Endpoint Results from the COMPARE 60/80 HBR Trial: A Randomized Controlled Multi-Center Trial Comparing Ultrathin With Thin Strut Stents in High Bleeding Risk Patients With an Abbreviated DAPT Duration |
Polymer-Free Amphilimus-Eluting Stents vs. Biodegradable-Polymer Everolimus-Eluting Stents in All-Comers Undergoing PCI: 1-Year Results of the PARTHENOPE Trial |
Long-Term Outcomes with Biodegradable Polymer Sirolimus-Eluting Stents Versus Durable Polymer Everolimus-Eluting Stents in Patients With ST-Segment Elevation Myocardial Infarction: 5-Year Follow-up of the Biostemi Randomized Trial | Long-term Clinical Outcomes After iFR vs. FFR Guided Coronary Revascularization – Insights From the SWEDEHEART National Registry |
Individual Patient-data Pooled Analysis of Endovascular Ultrasound Renal Denervation or a Sham Procedure at 6 Months in the RADIANCE
Clinical Trial Program | Recurrent Revascularization After Treatment Of Drug-Eluting Stent Restenosis With Drug-Coated Balloon, Plain Balloon Or Drug-Eluting Stent 10-Year Results From the Randomized ISAR-DESIRE 3 Trial |
Drug-Coated Balloon for Acute Coronary Syndromes: A Multicenter Randomized Non-inferiority Trial (DCB-ACS Trial) | Atrioventricular Conduction System Changes During Transcatheter Aortic Valve Replacement (TAVR): Anatomic and Electrophysiologic Predictors of Heart Block in Prospective 400 Patient EPS/TAVR Study |
Outcomes of Patients With New Left Bundle Branch Block Following Transcatheter Aortic Valve Replacement: Insights From the NCDR STS/ACC TVT Registry |
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Safety and Efficacy of Ticagrelor Monotherapy in Patients With Acute Coronary Syndrome Undergoing
Percutaneous Coronary Intervention: An Individual Patient Data Meta-analysis of the
TWILIGHT and TICO Randomized Trials |
Clopidogrel Monotherapy Following 1-month DAPT versus Aspirin Monotherapy Following 12-month DAPT in
Patients Receiving PCI; Final 5-year Result of STOPDAPT-2 |
Ten-Year Clinical Outcomes after PCI of a Concurrent Chronic Total Coronary Occlusion or Optimal Medical
Therapy Alone in Patients with STEMI: Extended Follow-Up of the EXPLORE trial |
Impact of High Bleeding Risk status on comparative outcomes of Physiology-guided Complete versus
Culprit-Only Revascularization in older MI patients: Data from the FIRE trial |
A Prospective, Observational, Single Arm, Multicenter Registry to evaluate clinical outcomes of the
Shockwave Coronary Intravascular Lithotripsy (IVL) followed by stent implantation in Calcified Coronary
Arteries in Real World Indian Patient Population (Shock India Registry) |
Rotational atherectomy combined with cutting balloon to optimize stent expansion in calcified lesions –
Primary Results of the ROTACUT trial |
OCT-Imaging Derived Parameters and Clinical Outcomes after PCI: The Pivotal ILUMIEN IV Trial |
Comparison between optical coherence tomography guidance and angiography guidance in percutaneous
coronary intervention (COCOA) |
Physiology Optimized Versus Angio-guided PCI (AQVA-II) |
Optical Coherence Tomography-Guided or Intravascular Ultrasound-Guided PCI for Complex Coronary-Artery
Lesions: A Key Analysis from the OCTIVUS Trial |
Impact of Intravascular Imaging in Patients with Acute Coronary Syndrome Undergoing Complex Percutaneous
Coronary Intervention: A prespecified substudy of the RENOVATE-COMPLEX-PCI |
Pullback Pressure Gradient Predicts Revascularization Outcomes: The PPG
Global Study |
First-In-Human Study of ShortCut Dedicated Transcatheter Leaflet Splitting Device |
Routine versus selective protamine administration to reduce bleeding in transcatheter aortic valve
implantation: ACE-PROTAVI |
Dual ProGlide versus ProGlide and AngioSeal for Hemostasis at the Femoral Access after Transcatheter
Aortic Valve Replacement: A Randomized Comparative Trial |
Balloon- vs. Self-Expanding valve systems for failed small surgical aortic valve bioprostheses: 1-year
results of the LYTEN trial |
Randomized Comparison of the Sapien and Myval Transcatheter Heart Valves: Device Regurgitation Assessed
by Cardiac Magnetic Resonance Imaging |
Commissural Alignment and Transcatheter Aortic Valve Performance: Results From the
COMALIGN-neo2
Study |
New Limus vs. Paclitaxel Coated Balloon Clinical Studies |
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Twelve-Month Follow-Up Outcomes of a Prospective, Multi-Center, Open, Single-Arm Study of the First
Everolimus-Coated Balloon for the Treatment of Coronary In-Stent Restenosis |
Treatment of Coronary De-Novo Lesions by a Sirolimus or a Paclitaxel Coated Balloon in a European
Population |
A Prospective, Multicenter, Randomized Trial Comparing Sirolimus-Coated Balloon with Paclitaxel-Coated
Balloon in De-Novo Small Vessels: The TRANSFORM I Trial |
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Emerging Concepts and Technological Trends in DCB Use |
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Drug-Coated Balloon for Acute Coronary Syndromes: A Multicenter Randomized Non-inferiority Trial (DCB-ACS
Trial) |
Drug-Eluting Balloon Treatment of Vulnerable Lipid-Rich Plaques: The DEBuT-LRP Study |
Drug-Coated Balloon Angioplasty For De Novo Lesions on Left Anterior Descending Artery |
Immediate and Follow-Up Outcomes of Drug-Coated Balloon Angioplasty in de Novo Long Lesions on Large
Coronary Arteries |
Featured Clinical Science in TAVR |
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Comparison of Two Self-Expanding Transcatheter Heart Valves for Degenerated Surgical Bioprostheses: The
AVENGER Multi-Center Registry |
Mortality Associated with Untreated Aortic Stenosis: Insights from Natural Language Process Big-Data
Based Real-World Database |
Endovascular Spotlight 3: Featured Clinical Science With Live Case |
Drug Eluting Stent or Primary Bare Nitinol Stent Application Versus Drug Coated Balloons in Long SFA
Lesions |
Percutaneous Transmural Bypass for Long and Complex Femoropopliteal Lesions: Clinical Outcomes of the
DETOUR-2 Study |
Real World Experience of Contemporary Pulmonary Embolism Treatment (USCDT versus MT): Insights From Big
Data Analytics (REAL-PE) |
Featured Clinical Science: AI-Based CT Coronary Imaging |
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Artificial Intelligence-Enabled Quantitative Plaque and Hemodynamic Analysis for Predicting Acute
Coronary Syndrome Risk and Prevention Strategy: The EMERALD II Study |
Safety and Feasibility of Planning and Performing Coronary Artery Bypass Surgery Guided Solely by
Coronary Computed Tomography Angiography |
Completeness of Revascularization by FFRCT: Association to Patient- and Vessel-Oriented Cardiac
Outcomes |
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Featured Clinical Science: New DES Systems and Other Coronary Technologies |
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A Randomized Clinical Trial of a Novel Triple Drug Eluting Coronary Implant Eluting Two Anticoagulants
and Sirolimus: Six-Month Clinical and Imaging Results of the DESyne BDS Plus Study |
First Human Use of a ‘Hybrid’ (Polymer + Metal) Coronary Drug-Eluting Stent: The IonMAN Study |
Coronary Sinus Reducer Improves Angina and Coronary Flow Reserve in Patients With Coronary Microvascular
Dysfunction |
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Featured Clinical Science in Peripheral Vascular Technologies |
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Intentional Coronary Revascularization Versus Conservative Therapy in Patients, who Underwent Successful
Peripheral Artery Revascularization due to Critical Limb Ischemia - the INCORPORATE Randomized Clinical
Trial |
Angiographic and Clinical Outcomes of the Thin-Strut MAGNITUDE Bioresorbable Scaffold in Patients with
Below-the-Knee Arterial Disease: Early Results from the RESOLV I Trial |
Deep Vein Arterialization for No-Option CLTI Patients: Technology and Clinical Program Update |
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Featured Clinical Science in Transcatheter Tricuspid Valve Intervention |
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Validation of the Kansas City Cardiomyopathy Questionnaire in Patients With Tricuspid Regurgitation: The
Tri-QOL Study |
TRILUMINATE Pivotal Imaging Substudy: Insights from CT and MRI |
Featured Clinical Science: Anticoagulation Post-LAAO |
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Keynote Lecture: Which Anticoagulant or Antiplatelet Regimen Post LAAO - The Present and
Future? |
Histomorphometric and Histopathologic Findings in Patients Undergoing Left Atrial Appendage Closure With
Use of a Double-Filter Embolic Protection Device |
Percutaneous Left Atrial Appendage Closure Versus Chronic Oral Anticoagulation for Non-Valvular Atrial
Fibrillation: An Individual Patient Data Level Meta-Analysis of Randomized Controlled Trials |
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Featured Clinical Science: New Generation LAAO Devices |
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US Early Feasibility Study Evaluating the Safety and Efficacy of Rotational Closure of the Left Atrial
Appendage Using the Laminar Device in Patients with Non-Valvular Atrial Fibrillation |
First-in-Human Experience with the Novel Watchman FLX Pro Device: Results of the Watchman FLX Pro CT
study |
Percutaneous Left Atrial Appendage Closure with the Lesifter Device for Stroke Prevention in Atrial
Fibrillation |
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Featured Clinical Science: Intravascular Imaging and Physiology |
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An Optical Coherence Tomography Guided Non-Stenting Reperfusion Strategy in Patients with STEMI— A Prospective, Multi-Centre, Observational Study (EROSION II) Haibo Jia |
Optical Coherence Tomography-based Functional Stenosis Assessment: FUSION - A Prospective Multi-Center
Trial |
Featured Clinical Science: Stroke and Cognitive Function After TAVR |
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Cardiac Output, Cerebral Blood Flow and Cognitive Functioning in Patients Undergoing Transcatheter Aortic
Valve Implantation |
Cerebral Microbleeds During Transcatheter Aortic Valve Replacement: A Prospective Magnetic Resonance
Imaging Study Cohort |
Brain Injury Volume by Diffusion Weighted MRI is Associated with Ischemic Stroke After TAVR: Results of a
Patient-Level Pooled Analysis |
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